Tongkat Ali leaves extract

By tongkatali.org
tongkataliorg3@gmail.com
Updated June 14, 2025

Apart from our unchanged-since-1998 Tongkat Ali 1:200 root extract, we also produce Tongkat Ali leaves extract, and we are the only company worldwide that does so on a commercial scale.

Compared to roots, leaves have 20-fold eurycomanone. Leaves contain more than 6 mcg eurycomanone per mL, roots just 0.3 mcg per mL
Source: Biotechnology Journal
https://journals.utm.my/
jurnalteknologi/
article
/view/6011.

Because of the high eurycomanone content in leaves, extracts that use leaves tend to spike testosterone synthesis, and on the short run are therefore more agitating than extracts without leaves. This can cause insomnia in some people.

As shown in scientific research, eurycomanone at higher dosages increases free testosterone via the inhibition of aromatase. Aromatase is an enzyme which breaks down circulating testosterone and converts it into estrogens. This is doubly awkward because not only does aromatase reduce bioavailable testosterone; it actually converts testosterone into anti-testosterone. Eurycomanone limits this reaction.

At high enough dosages, eurycomanone also acts as phosphodiesterase inhibitor. Mind you, drugs like sildenafil are phosphodiesterase inhibitors.

https://pubmed.ncbi.nlm.
nih.gov/23810842/